<p class="MsoNormal">Piperine is a chemical found in whole black pepper. The body seems to respond to this molecule in a variety of ways. It seems to lessen inflammation, ease pain, and enhance breathing. It's unclear how piperine enhances brain function, but it does appear to. People who have difficulty swallowing, want to stop smoking, or want to avoid falls may inhale black pepper oil. Black pepper and black pepper oil are spices that are added to meals.